O'Connell C M, Fried P A
Neurobehav Toxicol Teratol. 1984 Sep-Oct;6(5):345-50.
The offspring of 25 cannabis using women and the offspring of 25 matched controls were examined for the presence of a number of minor physical anomalies (MPA's). None of the anomalies noted occurred more frequently among the offspring of cannabis users. The number of anomalies present in an individual was not correlated with any of the maternal variables of cannabis, nicotine, or alcohol use or with maternal nutritional status during the first trimester. Children with "high" anomaly scores (i.e., more than three anomalies) had not experienced more fetal distress or neonatal difficulty than had children with low anomaly scores. Although a pattern of anomalies was not detected among the offspring of cannabis users, two anomalies, true ocular hypertelorism and severe epicanthus, were found only among children of heavy users of cannabis.
对25名使用大麻的女性的后代以及25名匹配对照组的后代进行了多项轻微身体异常（MPA）检查。在大麻使用者的后代中，所记录的异常情况均未更频繁地出现。个体出现的异常数量与母亲使用大麻、尼古丁或酒精的任何变量，或与孕早期的母亲营养状况均无关联。“高”异常评分（即超过三种异常）的儿童相比“低”异常评分的儿童，并未经历更多的胎儿窘迫或新生儿困难。尽管在大麻使用者的后代中未检测到异常模式，但仅在大量使用大麻的母亲的孩子中发现了两种异常，即真性眼距过宽和严重内眦赘皮。
