Petrenko A Iu, Belous A M, Novgorodov S A, Marshanskiĭ V N, Iaguzhinskiĭ L S
Ukr Biokhim Zh (1978). 1984 Nov-Dec;56(6):651-6.
Induction of ion transport in the rat liver mitochondria arising after their deep freezing is inhibited effectively by adenosine diphosphate, Mg ions, Ca2+ complexons (EDTA, EGTA) as well as by inhibitors of ATPase (oligomycin and dicyclohexylcarbodiimide) and of electrogenic transport of Ca2+ (ruthenium red). The value of ion flows is determined by adenine nucleotide concentration in the matrix. It is supposed that specific inhibitors of ion electrogenic transport promoting an increase in the transmembrane potential prevent from releasing adenine nucleotides from the mitochondrial matrix.
大鼠肝脏线粒体深度冷冻后出现的离子转运诱导作用，可被二磷酸腺苷、镁离子、钙离子络合剂（乙二胺四乙酸、乙二醇双乙醚二胺四乙酸）以及三磷酸腺苷酶抑制剂（寡霉素和二环己基碳二亚胺）和钙离子电致转运抑制剂（钌红）有效抑制。离子流的值由基质中的腺嘌呤核苷酸浓度决定。据推测，促进跨膜电位升高的离子电致转运特异性抑制剂可阻止腺嘌呤核苷酸从线粒体基质中释放。
