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[小鼠神经母细胞瘤C 1300细胞分化过程中脂质成分的变化]

[Changes in the lipid composition of murine neuroblastoma C 1300 cells during the process of differentiation].

作者信息

Gulaia N M, Volkov G L, Govseeva N N, Artemenko I P, Latyshev N A

出版信息

Ukr Biokhim Zh (1978). 1984 Nov-Dec;56(6):677-81.

PMID:6515738
Abstract

The paper deals with the lipid composition of nondifferentiated cells at the logarithmic and stationary growth phases as well as with differentiated cells of C 1300 neuroblastoma adopted to the Eagle medium. It is shown that phospholipids and cholesterol dominate at the studied growth phases among lipids. Their amount in the differentiation process is thrice as high calculating per cells. The quantity of individual phospholipids changes in different manner during differentiation. The phosphatidylinosite level is higher than of other substances.

摘要

本文研究了处于对数生长期和稳定期的未分化细胞以及适应于伊格尔培养基的C 1300神经母细胞瘤分化细胞的脂质组成。结果表明,在所研究的生长阶段,磷脂和胆固醇在脂质中占主导地位。按细胞计算,它们在分化过程中的含量是原来的三倍。在分化过程中,个别磷脂的数量变化方式不同。磷脂酰肌醇的水平高于其他物质。

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[Changes in the lipid composition of murine neuroblastoma C 1300 cells during the process of differentiation].[小鼠神经母细胞瘤C 1300细胞分化过程中脂质成分的变化]
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