Keller F, Knöfler W, Schreiber H, Hess J, Wohlgemuth B
Z Exp Chir Transplant Kunstliche Organe. 1984;17(6):330-6.
The subsidence process of the tissue reaction was estimated by the thickness of the fibrous capsule as well as different histologic characteristics in dependence on the period after the implantation of 4 several implant materials. This subsidence process was fitted mathematically by an exponential function respectively a power function by means of the regression analysis. The power function described best the experimentally found curve. The correspondence, on principle, of the subsidence process of the fibrous capsula thickness on the one hand and the 9 histologic characteristics on the other hand could be proved. A standard valuation for subcutaneous tests is demanded which include the designation of the thickness of the fibrous capsula as well as characteristic cell type frequencies as histologic characteristics.
通过纤维囊的厚度以及植入4种不同植入材料后不同时间段的不同组织学特征，对组织反应的沉降过程进行了评估。通过回归分析，分别用指数函数和幂函数对该沉降过程进行数学拟合。幂函数最能描述实验得到的曲线。一方面可以证明纤维囊厚度的沉降过程与另一方面9种组织学特征在原则上的对应关系。需要一种皮下试验的标准评估方法，该方法应包括将纤维囊的厚度以及特征性细胞类型频率指定为组织学特征。
