Le Mapihan Y, Pierrot M, Khenifer L, Fournier J L, Cupa M
Acta Anaesthesiol Belg. 1984;35 Suppl:415-22.
The danger of the anaphylactoid reactions which occur during pediatric general anesthesia leads the authors to use a specific antihistaminic premedication. The association of cimetidine and hydroxizine has been proved to be adequate to avoid systemic histamine adverse effects and to diminish gastric secretion in pediatric anesthesia. The authors recommend oral administration.
小儿全身麻醉期间发生类过敏反应的风险促使作者使用特定的抗组胺药进行术前用药。已证明西咪替丁和羟嗪联合使用足以避免全身性组胺不良反应,并减少小儿麻醉期间的胃液分泌。作者建议口服给药。