Colangelo P M, Welch D W, Rich D S, Jeffrey L P
Am J Hosp Pharm. 1984 Dec;41(12):2650-5.
Two methods for estimating body surface area (BSA) in adult amputees were developed. BSA in sq m was determined in 42 healthy, nonamputee men and women by summing the surface areas of individual body parts obtained using geometric measurements (BSAmeas) and by an equation using height and weight (BSAcalc). Linear regression analysis was used to determine correlations between BSAmeas and BSAcalc and between BSAmeas and surface-area measurements of individual body parts (SApart). The percentages of total BSA contributed by individual body parts in each subject were determined by the ratio of SApart to BSAmeas, and these percentages were compared with the corresponding percentages for body parts using the "Rule of Nines." BSAcalc and BSAmeas were significantly correlated, as were SApart and BSAmeas. Regression analysis of SApart versus BSAmeas yielded an equation for each measured body part that allowed calculation of SApart without direct measurement. SApart expressed as a percentage of total BSA differed from the percentage of BSA used in the "Rule of Nines" by a mean of 12.4-32% depending on the body part. Two methods of estimating BSA in amputees were proposed based on deduction of the surface area of the amputated part (calculated from the regression equation for SApart or as a percentage of total BSA) from total BSAcalc in adult amputees. The two methods developed in this study for estimating BSA may be useful in determining drug dosages in adult amputees and may provide more accurate information in burn therapy. Further studies are needed to validate the clinical application of these methods.
开发了两种用于估计成年截肢者体表面积（BSA）的方法。通过将使用几何测量获得的各个身体部位的表面积相加（BSAmeas）以及使用身高和体重的公式（BSAcalc），对42名健康的非截肢男性和女性的体表面积（以平方米为单位）进行了测定。采用线性回归分析来确定BSAmeas与BSAcalc之间以及BSAmeas与各个身体部位的表面积测量值（SApart）之间的相关性。通过SApart与BSAmeas的比值确定每个受试者中各个身体部位占总BSA的百分比，并将这些百分比与使用“九分法”的身体部位相应百分比进行比较。BSAcalc与BSAmeas显著相关，SApart与BSAmeas也显著相关。对SApart与BSAmeas进行回归分析，得出了每个测量身体部位的一个方程，该方程允许在不进行直接测量的情况下计算SApart。根据身体部位的不同，SApart占总BSA的百分比与“九分法”中使用的BSA百分比平均相差12.4 - 32%。基于从成年截肢者的总BSAcalc中减去截肢部位的表面积（根据SApart的回归方程计算或作为总BSA的百分比），提出了两种估计截肢者BSA的方法。本研究中开发的两种估计BSA的方法可能有助于确定成年截肢者的药物剂量，并且在烧伤治疗中可能提供更准确的信息。需要进一步的研究来验证这些方法的临床应用。
