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偶然分枝杆菌生物变种偶然型及未命名的第三生物变种复合体对重金属盐的敏感性。

Susceptibilities of Mycobacterium fortuitum biovariant fortuitum and the unnamed third biovariant complex to heavy-metal salts.

作者信息

Wallace R J, Steele L C, Forrester G D, Swenson J M, Hull S I

出版信息

Antimicrob Agents Chemother. 1984 Oct;26(4):594-6. doi: 10.1128/AAC.26.4.594.

DOI:10.1128/AAC.26.4.594
PMID:6517549
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC179972/
Abstract

Fifty-three clinical isolates of Mycobacterium fortuitum were tested for susceptibility to heavy-metal salts and antimicrobial agents. The isolates exhibited a bimodal distribution for several heavy metals including mercury, whose resistance is often plasmid mediated. There was a biovariant difference in the incidence of resistance, and resistance to several metal ions was often observed together. There was no apparent relationship between resistance to heavy-metal salts and resistance to antimicrobial agents such as tetracycline.

摘要

对53株偶然分枝杆菌临床分离株进行了重金属盐和抗菌剂敏感性测试。这些分离株对包括汞在内的几种重金属呈现双峰分布，其耐药性通常由质粒介导。耐药发生率存在生物变种差异，并且经常同时观察到对几种金属离子的耐药性。对重金属盐的耐药性与对四环素等抗菌剂的耐药性之间没有明显关系。

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本文引用的文献

1
Identification of clinically significant Mycobacterium fortuitum complex isolates.具有临床意义的偶然分枝杆菌复合群菌株的鉴定。
J Clin Microbiol. 1981 Dec;14(6):686-91. doi: 10.1128/jcm.14.6.686-691.1981.
2
Inducible plasmid-determined resistance to arsenate, arsenite, and antimony (III) in escherichia coli and Staphylococcus aureus.大肠杆菌和金黄色葡萄球菌中由质粒介导的对砷酸盐、亚砷酸盐和锑（III）的诱导抗性
J Bacteriol. 1981 Jun;146(3):983-96. doi: 10.1128/jb.146.3.983-996.1981.
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Rapidly growing mycobacteria: testing of susceptibility to 34 antimicrobial agents by broth microdilution.快速生长分枝杆菌：采用肉汤微量稀释法检测对34种抗菌药物的敏感性
Antimicrob Agents Chemother. 1982 Aug;22(2):186-92. doi: 10.1128/AAC.22.2.186.
4
Presence of aminoglycoside acetyltransferase and plasmids in Mycobacterium fortuitum. Lack of correlation with intrinsic aminoglycoside resistance.偶然分枝杆菌中氨基糖苷乙酰转移酶和质粒的存在。与固有氨基糖苷耐药性缺乏相关性。
Am Rev Respir Dis. 1984 Apr;129(4):614-8.
5
Plasmid-encoded mercuric reductase in Mycobacterium scrofulaceum.瘰疬分枝杆菌中的质粒编码汞还原酶。
J Bacteriol. 1984 Feb;157(2):669-72. doi: 10.1128/jb.157.2.669-672.1984.
6
Spectrum of disease due to rapidly growing mycobacteria.快速生长分枝杆菌所致疾病谱
Rev Infect Dis. 1983 Jul-Aug;5(4):657-79. doi: 10.1093/clinids/5.4.657.
7
In vitro susceptibility of human and environmental isolates of Mycobacterium avium, M. intracellulare, and M. scrofulaceum to heavy-metal salts and oxyanions.鸟分枝杆菌、胞内分枝杆菌和瘰疬分枝杆菌的人体及环境分离株对重金属盐和含氧阴离子的体外敏感性。
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Disk diffusion testing of susceptibility of Mycobacterium fortuitum and Mycobacterium chelonei to antibacterial agents.偶然分枝杆菌和龟分枝杆菌对抗菌剂敏感性的纸片扩散试验
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