Cherbut C, Ruckebusch Y
Gastroenterol Clin Biol. 1984 Dec;8(12):955-9.
The relationship between undigestible particle intake and myoelectric activity of the colon was examined in three dogs fed with a low-fiber diet alone or with polyethylene particles containing 10 p. 100 and 45 p. 100 of dry matter. When compared to controls colonic electromyograms of dogs fed on polyethylene revealed a 40 p. 100 reduction in long spike bursts (LSBs). The sequences of LSBs propagated over long distances, or MSBs (migrating spike bursts) were unchanged and only the myoelectric activity corresponding to LSBs propagated for very short distances was abolished by polyethylene diets. Concurrently, the percentage of water excreted in the feces was increased. Undigestible and inert particles were thus able to modify the colonic motor profile and to increase the fecal excretion of water. Such effects were similar to those observed with dietary fibers. It is suggested that dietary fiber effects on fecal excretion and colonic motility are partially induced by their mechanical action on the intestinal wall. In addition, the absence of LSBs propagated in both directions and for short distances on the canine proximal and transverse colons seems to be a limiting factor in the movements of water absorption.
在三只仅喂食低纤维饮食或喂食含有10%、100%和45%干物质的聚乙烯颗粒的狗身上，研究了不可消化颗粒摄入量与结肠肌电活动之间的关系。与对照组相比，喂食聚乙烯的狗的结肠肌电图显示长尖峰爆发（LSBs）减少了40%。LSBs的序列在长距离传播，即迁移性尖峰爆发（MSBs）没有变化，只有与LSBs相对应的肌电活动在短距离传播被聚乙烯饮食消除。同时，粪便中排出的水分百分比增加。因此，不可消化和惰性颗粒能够改变结肠运动模式并增加粪便中的水分排泄。这种作用与膳食纤维观察到的作用相似。有人提出，膳食纤维对粪便排泄和结肠运动的影响部分是由它们对肠壁的机械作用引起的。此外，犬近端和横结肠上双向和短距离传播的LSBs的缺失似乎是水分吸收运动的一个限制因素。
