Zussa C, Galloni M R, Zattera G F, Pansini S, di Summa M, Poletti G A, Ottino G, Morea M
Int J Cardiol. 1984 Dec;6(6):719-35. doi: 10.1016/0167-5273(84)90299-7.
We studied 13 porcine bioprostheses removed from patients with endocarditis at our institute during the last 4.5 years. All bioprostheses had been removed at reoperation and were analyzed using anatomical and histological techniques. Each bioprosthesis was found to have developed rather constant lesions which were not related to the type of bioprosthesis. The stage of infection was not related to the duration of implantation. The presence of perivalvular abscesses was an ominous finding, often being the seat of persistent endocarditis. Our good clinical results of reoperation lead us to suggest that this be performed early once valvular or prosthetic malfunction is detected. Bioprostheses are, in our experience, the best choice in the surgical treatment of prosthetic valve endocarditis.
我们研究了过去4.5年里从我院心内膜炎患者身上取出的13个猪生物瓣膜。所有生物瓣膜均在再次手术时被取出，并采用解剖学和组织学技术进行分析。发现每个生物瓣膜都出现了相当恒定的病变，且这些病变与生物瓣膜的类型无关。感染阶段与植入时间长短无关。瓣周脓肿的存在是一个不祥的发现，常是持续性心内膜炎的病灶所在。我们再次手术取得的良好临床效果促使我们建议，一旦检测到瓣膜或人工瓣膜功能障碍，应尽早进行再次手术。根据我们的经验，生物瓣膜是人工瓣膜心内膜炎外科治疗的最佳选择。
