Golikov A P, Zvereva T V, Polumiskov V Iu, Avilova O A
Kardiologiia. 1984 Sep;24(9):47-50.
The formation of the myocardial necrotic focus was assessed by precardial charting at 35 leads and the serial determination of CPK activity and MB fraction in 50 patients receiving the systemic thrombolytic therapy and 52 patients of the control group. Thrombolytic therapy initiated within the first 6 h of the disease was shown to facilitate the limitation of the extent of myocardial infarction through a more rapid stabilization of the necrotic focus. The calculated extent of myocardial infarction in patients treated with thrombolytic drugs was 37.4% less than in the control group. A beneficial clinical effect of thrombolytic therapy was demonstrated.
通过对50例接受全身溶栓治疗的患者和52例对照组患者进行35导联的心前区绘图以及连续测定肌酸磷酸激酶（CPK）活性和MB组分，评估心肌坏死灶的形成情况。结果显示，在疾病发病后6小时内开始的溶栓治疗可通过更快地稳定坏死灶来促进限制心肌梗死的范围。接受溶栓药物治疗的患者计算得出的心肌梗死范围比对照组小37.4%。溶栓治疗显示出有益的临床效果。
