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视网膜色素上皮失代偿。I. 临床特征与自然病程。

Retinal pigment epithelium decompensation. I. Clinical features and natural course.

作者信息

Jalkh A E, Jabbour N, Avila M P, Trempe C L, Schepens C L

出版信息

Ophthalmology. 1984 Dec;91(12):1544-8. doi: 10.1016/s0161-6420(84)34095-7.

DOI:10.1016/s0161-6420(84)34095-7
PMID:6521993
Abstract

We studied 97 eyes (73 patients) that showed a sharp contrast between the grossly normal appearance of the posterior pole by funduscopy and the fluorescein angiography findings of multiple patches of retinal pigment epithelium (RPE) transmission defect in the early transit, associated with focal areas of RPE staining in the late transit. The staining was located primarily at the superior edge of the RPE defect (63 eyes). The average age of the patients was 52.2 years at the time of diagnosis, and the ratio of men to women was 3.5 to 1. Ocular histories were unremarkable, except for 27 eyes with documented central serous retinopathy. Thirty-two consecutive eyes have been followed for an average of 3.9 years, and 30 of those eyes have shown visual deterioration.

摘要

我们研究了97只眼(73例患者),这些眼通过眼底镜检查显示后极部外观大致正常,与早期造影时多个视网膜色素上皮(RPE)透见缺损斑以及晚期造影时RPE局限性染色形成鲜明对比。染色主要位于RPE缺损的上缘(63只眼)。诊断时患者的平均年龄为52.2岁,男女比例为3.5比1。除27只眼有中心性浆液性视网膜病变记录外,眼部病史无异常。连续32只眼平均随访3.9年,其中30只眼出现视力下降。

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