视网膜色素上皮失代偿。二、激光治疗。

Retinal pigment epithelium decompensation. II. Laser treatment.

作者信息

Jalkh A E, Jabbour N, Avila M P, Trempe C L, Schepens C L

出版信息

Ophthalmology. 1984 Dec;91(12):1549-53. doi: 10.1016/s0161-6420(84)34118-5.

Abstract

Forty-one of 97 eyes with retinal pigment epithelium decompensation (RPED) were treated with monochromatic green argon laser photocoagulation to the focal area of RPE staining detected in the late fluorescein transit. Nineteen eyes were treated because of progressive visual deterioration. The other 22 eyes already had visual acuities of 20/50 or worse. Vision stabilized or improved in 34 eyes (82.9%) after an average of 1.6 years following treatment, compared with improvement in only 5 of 56 untreated eyes after an average follow-up period of 2.1 years. After an average follow-up of 7.1 years, 12 of 97 eyes with RPED developed choroidal neovascularization (9 spontaneously and 3 after photocoagulation) in the area where late RPE staining had been observed.

摘要

97只患有视网膜色素上皮失代偿（RPED）的眼睛中，41只眼睛在荧光素晚期发现的视网膜色素上皮（RPE）染色病灶区域接受了单色绿色氩激光光凝治疗。19只眼睛因视力进行性下降而接受治疗。另外22只眼睛的视力已经在20/50或更差。治疗后平均1.6年，34只眼睛（82.9%）的视力稳定或改善，相比之下，56只未治疗的眼睛在平均随访2.1年后只有5只眼睛视力改善。平均随访7.1年后，97只患有RPED的眼睛中有12只在曾观察到晚期RPE染色的区域发生了脉络膜新生血管（9只为自发发生，3只为光凝后发生）。