Kjorstad K E, Orjaseter H
Obstet Gynecol. 1978 May;51(5):536-40. doi: 10.1097/00006250-197805000-00004.
A modified CEA-Roche kit was used to determine the pretreatment value of carcinoembryonic antigen (CEA) in patients with intraepithelial neoplasia and invasive squamous cell carcinoma of the cervix. A positive correlation between tumor volume and CEA levels was found in patients with invasive disease, and patients with intraepithelial neoplasia also had elevated levels compared with a reference material of blood donors. Pre- and posttreatment levels were measured in 156 patients with invasive lesions, and a significant response to treatment was seen in 80%. The resutls of this study indicate that any pretreatment level can be of interest in the followup of patients with squamous cell carcinoma of the cervix.
采用改良的癌胚抗原罗氏检测试剂盒测定宫颈上皮内瘤变和浸润性鳞状细胞癌患者癌胚抗原（CEA）的治疗前值。在浸润性疾病患者中发现肿瘤体积与CEA水平呈正相关，与献血者参考材料相比，上皮内瘤变患者的CEA水平也有所升高。对156例浸润性病变患者进行了治疗前和治疗后的水平测定，80%的患者对治疗有显著反应。本研究结果表明，在宫颈鳞状细胞癌患者的随访中，任何治疗前水平都可能具有重要意义。
