van Nagell J R, Meeker W R, Parker J C, Kashmiri R, McCollum V
Am J Obstet Gynecol. 1976 Sep 1;126(1):105-9. doi: 10.1016/0002-9378(76)90473-7.
Carcinoembryonic antigen (CEA) was elevated (greater than 2.5 ng. per milliliter) in 29 of 100 patients with cervical intraepithelial neoplasia (CIN). CEA concentration was related to the amount of intraepithelial neoplasia and to the presence of glandular extension. Lymphoplasmacytic infiltration of tumor cells was unrelated to CEA levels. CEA values returned to normal within 8 weeks following surgery in 77 per cent of patients. A persistently elevated (greater than 5.0 ng. milliter) plasma CEA value following conization was associated with residual CIN in the cervix. These results suggest that sequential CEA determinations may be of value in the follow-up of those cervical cancer patients who initially have high plasma antigen levels.
100例宫颈上皮内瘤变（CIN）患者中，29例癌胚抗原（CEA）升高（大于2.5纳克/毫升）。CEA浓度与上皮内瘤变的程度及腺性延伸的存在有关。肿瘤细胞的淋巴浆细胞浸润与CEA水平无关。77%的患者术后8周内CEA值恢复正常。锥切术后血浆CEA值持续升高（大于5.0纳克/毫升）与宫颈残留CIN有关。这些结果表明，对于那些最初血浆抗原水平较高的宫颈癌患者，连续测定CEA可能对随访有价值。
