Sloth Madsen P, Strøm J, Reiz S, Bredgaard Sørensen M
Acta Anaesthesiol Scand. 1984 Dec;28(6):661-5. doi: 10.1111/j.1399-6576.1984.tb02141.x.
The course of severe propoxyphene self-poisoning in 222 consecutive patients is presented. On admission, 73% of the patients had neurological symptoms, 10% had convulsions, 45% were in respiratory failure, and impaired circulation was present in 48%. A mortality rate of 8% was observed. Twelve patients arrived in asystole of whom six were resuscitated without sequelae. The overdose was accidental in 13 patients, one of whom died. Early medical intensive care was found mandatory for a good prognosis. Before discharge from the ICU we recommend an observation-period free of cardiovascular symptoms for 24 h.
本文介绍了222例连续的严重丙氧芬自中毒患者的病程。入院时，73%的患者有神经症状，10%有惊厥，45%处于呼吸衰竭，48%存在循环障碍。观察到的死亡率为8%。12例患者入院时心跳骤停，其中6例复苏成功且无后遗症。13例患者过量用药为意外，其中1例死亡。发现早期医学重症监护对良好预后至关重要。在从重症监护病房出院前，我们建议有24小时无心血管症状的观察期。
