Matovelo J A, Landsverk T, Amaya Posada G
Acta Vet Scand. 1984;25(3):322-6. doi: 10.1186/BF03547246.
Trophozoites, gametes, and schizonts characteristic of Cryptosporidia were demonstrated in 2 Tanzanian goat kids. In a heavily infected kid the parasite was associated with villous atrophy and crypt hyperplasia. An enhanced epithelial cell ageing and extrusion rate, possibly due to a drain on cell metabolites by the parasite, is suggested. The protozoan seemed to induce host cell specializations, including parasitophorous envelope and development of smooth-membraned vesicles. The vesicles possibly have a function in the transport of nutrients from the host cell to the parasite.
在2只坦桑尼亚山羊幼崽中发现了隐孢子虫的滋养体、配子和裂殖体。在一只重度感染的幼崽中,寄生虫与绒毛萎缩和隐窝增生有关。有人提出,上皮细胞衰老和挤出率增加可能是由于寄生虫消耗细胞代谢产物所致。这种原生动物似乎能诱导宿主细胞特化,包括形成寄生泡和光滑膜泡。这些泡可能在将营养物质从宿主细胞转运到寄生虫的过程中发挥作用。