Levi J U, Martinez O V, Malinin T I, Zeppa R, Livingstone A, Hutson D, Calhoun P
Antimicrob Agents Chemother. 1984 Dec;26(6):944-6. doi: 10.1128/AAC.26.6.944.
The biliary penetration of cefamandole was studied in six patients with total biliary obstruction before and after placement of a transhepatic bile drainage catheter. Biliary levels of cefamandole remained depressed even when the drug was administered as late as 7 days after decompression of the biliary tract.
在六名患有完全性胆道梗阻的患者中,于放置经肝胆汁引流导管前后,研究了头孢孟多的胆汁穿透情况。即便在胆道减压7天后才给药,头孢孟多的胆汁水平仍持续降低。