Sgaragli G P, Della Corte L, Giovannini M G, Ninci R, Franco C, Nardini M
Boll Soc Ital Biol Sper. 1984 Sep 30;60(9):1757-63.
Nanogram amounts of chlorimipramine, chlorpromazine and their Nor1- and Nor2-metabolites were detected in plasma by GLC with nitrogen-sensitive detection. Two extraction procedures were compared. The use of Sep Pak C18 cartridges produced a higher degree of accuracy and precision with significant time and materials saving, as compared to the use of organic solvents in a three steps extraction procedure.
采用带氮敏检测的气相色谱法在血浆中检测到纳克量的氯米帕明、氯丙嗪及其N-1和N-2代谢物。比较了两种提取方法。与三步有机溶剂提取法相比，使用Sep Pak C18柱提取具有更高的准确度和精密度，且显著节省时间和材料。
