Frati E, Castagna M L, Bacarelli M R, Fioravanti A, Giordano N, Taddeo A, Marcolongo R
Boll Soc Ital Biol Sper. 1984 Sep 30;60(9):1791-6.
The authors have examined the levels of the plasma cholesterol and triglycerides, of the plasma lipoproteins (HDL, LDL, VLDL) and of their main apolipoproteins (apo-A and apo-B) in a group of 64 patients affected by RA and in a population of healthy subjects considered as a contrast group, trying to establish a plausible dislipidemic factor which could justify the major occurrence of coronary heart disease in those patients suffering from RA. Statistical analysis was done with the T-test. There are not differences in the lipoprotein pattern between the group of patients affected by RA and the population of healthy subjects. The obtained result seem to exclude that such a major occurrence of coronary heart disease in the patients suffering from RA may be linked to the alteration of lipidic metabolism.
作者检测了64例类风湿关节炎患者以及作为对照的健康人群的血浆胆固醇、甘油三酯、血浆脂蛋白（高密度脂蛋白、低密度脂蛋白、极低密度脂蛋白）及其主要载脂蛋白（载脂蛋白A和载脂蛋白B）水平，试图确定一个合理的血脂异常因素，以解释类风湿关节炎患者冠心病高发的原因。采用t检验进行统计分析。类风湿关节炎患者组与健康人群的脂蛋白模式没有差异。所得结果似乎排除了类风湿关节炎患者冠心病高发可能与脂质代谢改变有关的可能性。
