Price M L
Hum Nutr Appl Nutr. 1984 Dec;38(6):409-15.
The underlying cause of atopic eczema remains unknown but both food intolerance and dietary deficiency--notably of essential fatty acids--may well be exacerbating factors. Studies investigating the involvement of food intolerance have shown that only some children obtain benefit from avoiding milk and eggs. In other cases, the use of an elimination or of a chemically-defined diet followed by challenge with specific foods may allow an effective personalized diet to be devised. Skin-prick tests and measurement of IgE levels have proved to be unreliable predictors of reactions to food. The development of a reliable test to assess food intolerance would represent a significant advance in the treatment of atopic eczema.
特应性湿疹的根本病因尚不清楚,但食物不耐受和饮食缺乏(尤其是必需脂肪酸缺乏)很可能是加剧因素。调查食物不耐受影响的研究表明,只有部分儿童通过避免食用牛奶和鸡蛋而受益。在其他情况下,采用排除饮食或化学定义饮食,随后对特定食物进行激发试验,可能有助于设计出有效的个性化饮食方案。皮肤点刺试验和IgE水平测量已被证明是食物反应的不可靠预测指标。开发一种可靠的测试方法来评估食物不耐受,将代表特应性湿疹治疗的重大进展。