Belghiti J
J Chir (Paris). 1984 Nov;121(11):681-4.
In surgical patients, the development of post operative sepsis and the high rate of mortality may be related to defects in host immune mechanisms. The presence of anergy defines patients with a high rate of sepsis and mortality. Factors know to depress cell mediated immunity are essentially malignancy and sepsis. Those two factors are often associated with protein calorie malnutrition. The presence of anergy require further explorations in order to discover disseminated malignancy and/or latent sepsis. Those two factors are the major determinant of post operative risks.
在外科手术患者中,术后脓毒症的发生及高死亡率可能与宿主免疫机制缺陷有关。无反应性的存在表明患者发生脓毒症和死亡的几率较高。已知抑制细胞介导免疫的因素主要是恶性肿瘤和脓毒症。这两个因素常与蛋白质热量营养不良相关。无反应性的存在需要进一步探究,以发现播散性恶性肿瘤和/或潜在脓毒症。这两个因素是术后风险的主要决定因素。