Awbrey B J, Jacobson P C, Grubb S A, McCartney W H, Vincent L M, Talmage R V
J Orthop Res. 1984;2(4):314-21. doi: 10.1002/jor.1100020402.
This is a cross-sectional study of bone densitometry in greater than 700 normal healthy white women ranging in age from 18 to 98 years. A modified procedure for single-photon bone density analysis of the distal radius is described and compared with dual-photon densitometric measurements of the second through fourth lumbar vertebrae. The distal radial site measured was separated from the ulna by 5 mm. This "5 mm" site was characterized according to trabecular and cortical bone content, measurement reproducibility, positioning precision, and the effects of wrist pronation or supination. The radial site demonstrated a bone density loss of less than 0.1%/year for normal women 25-50 years of age, increasing to 0.7%/year after 50 years of age. In contrast to the variability and inconsistency obtained by us and others utilizing the standard "9/10" site, bone loss with age at the new "5 mm" site correlated closely with generalized bone mineral loss of the axial skeleton. We suggest that there is a unique role for single-beam densitometric measurements of the radius, permitting the rapid and relatively inexpensive evaluation of large populations of women without requiring a visit to a medical center. Such a process can select those requiring further evaluation or medical attention.
这是一项针对700多名年龄在18至98岁之间的正常健康白人女性进行的骨密度横断面研究。本文描述了一种改良的桡骨远端单光子骨密度分析方法，并将其与第二至第四腰椎的双光子骨密度测量结果进行比较。所测量的桡骨远端部位与尺骨相隔5毫米。根据小梁骨和皮质骨含量、测量重复性、定位精度以及手腕旋前或旋后的影响，对这个“5毫米”部位进行了特征描述。对于25至50岁的正常女性，桡骨部位的骨密度每年下降不到0.1%，50岁以后则增至每年0.7%。与我们及其他人使用标准“9/10”部位所获得的变异性和不一致性相反，新“5毫米”部位的骨量随年龄减少与轴向骨骼的全身骨矿物质流失密切相关。我们认为，桡骨单束骨密度测量具有独特作用，无需前往医疗中心，就能对大量女性进行快速且相对廉价的评估。这样一个过程可以筛选出那些需要进一步评估或医疗关注的女性。
