Yasuna O, Hatayama Y, Karibe T, Ookura M, Munakata Y, Nishimaki K, Koike H, Yamaura Y, Ogiwara M
Gan No Rinsho. 1984 Dec;30(15):1893-8.
The incidence of associated synchronous or heterochronous malignant tumors in this series was 3.3% (21/633). These patients were found more in multiple cancer than single cancer of the stomach. A relatively high incidence of associated cancer of other organs was found with cancer of the large bowel and of the cervix in heterochronous cancer and cancer of the esophagus in synchronous tumors. The cumulative corrected 10-year survival rate of 15 cases of heterochronous tumors was 85.7%. On the other hand, six patients with synchronous tumor had more advanced cancer of other organs than gastric cancer, and four of them died due to cancer of other organs within two years. Both primaries should be found at the early stage and treated with curative surgery and/or radiotherapy.
在该系列中，相关同步或异时性恶性肿瘤的发生率为3.3%（21/633）。这些患者中发现多原发癌的比胃单发癌的更多。在异时性癌中，发现与大肠癌和宫颈癌相关癌的发生率相对较高，在同步肿瘤中与食管癌相关癌的发生率相对较高。15例异时性肿瘤患者的累计校正10年生存率为85.7%。另一方面，6例同步肿瘤患者其他器官的癌症比胃癌更晚期，其中4例在两年内因其他器官的癌症死亡。两个原发癌均应在早期发现，并采用根治性手术和/或放疗进行治疗。
