Hayasaka S, Honda M, Kitaoka M, Chiba R
Jpn J Ophthalmol. 1984;28(3):254-8.
We examined ophthalmologically five affected members of a family with type IIa hyperlipoproteinemia. All of them had increased levels of cholesterol and low-density lipoprotein. Corneal arcus was found in three of the five members; a 50-year-old man, a 43-year-old woman and a 13-year-old boy. We believe that the corneal arcus begins at around 10 years of age in untreated type IIa hyperlipoproteinemia. Detection of corneal arcus at an early age is important to reduce cardiovascular complication in this disorder.
我们对一个患有IIa型高脂蛋白血症家族的五名患病成员进行了眼科检查。他们所有人的胆固醇和低密度脂蛋白水平都有所升高。在五名成员中的三名身上发现了角膜弓；一名50岁男性、一名43岁女性和一名13岁男孩。我们认为，在未经治疗的IIa型高脂蛋白血症中，角膜弓大约在10岁左右开始出现。在早期检测到角膜弓对于减少这种疾病的心血管并发症很重要。
