Fryer J N, Ogilvie D M
Pharmacol Biochem Behav. 1978 Feb;8(2):129-32. doi: 10.1016/0091-3057(78)90328-3.
Guppies were exposed for 30 min to doses of 5-HT ranging from 20 to 120 mg/l, and then tested in a horizontal temperature gradient. Atlantic salmon injected with 2 microgram/g of 5-HT were similarly tested. The guppies exhibited a biphasic relationship between 5-HT dose and mean selected temperature, i.e., the lowest dose significantly decreased the selected temperature, while the highest dose significantly increased it. In the salmon, injection of 5-HT initially decreased the selected temperature by about 4 degrees C. With time, however, the selected temperature gradually increased until by three hours after injection it exceeded the control value by about 1.5 degrees C. This pattern of temperature change is similar to that observed with rabbits subjected to both systemic and central injection of 5-HT.
将孔雀鱼暴露于浓度范围为20至120毫克/升的5-羟色胺（5-HT）中30分钟，然后在水平温度梯度中进行测试。同样对注射了2微克/克5-羟色胺的大西洋鲑鱼进行测试。孔雀鱼在5-羟色胺剂量与平均选择温度之间呈现双相关系，即最低剂量显著降低了选择温度，而最高剂量则显著提高了选择温度。在鲑鱼中，注射5-羟色胺最初使选择温度降低了约4摄氏度。然而，随着时间的推移，选择温度逐渐升高，直到注射后三小时超过对照值约1.5摄氏度。这种温度变化模式与对兔子进行全身和中枢注射5-羟色胺时观察到的模式相似。
