Wing J K, Mann S A, Leff J P, Nixon J M
Psychol Med. 1978 May;8(2):203-17. doi: 10.1017/s0033291700014264.
A series of in-patients, a series of out-patients and a series of women from a general population sample, all aged under 65, and all living in the same area of south-east London, were examined using the ninth edition of the Present State Examination (PSE). An 'index of definition' (ID), based on number, type and severity of PSE symptoms, was constructed in order to define a threshold point above which sufficient information was available to allow classification into one of the functional psychoses or neuroses. The index specified 8 levels of definition of disorder; the threshold point for a 'case' lying between levels 4 and 5. The identification of 'cases' by this means in the general population series was highly concordant with global clinical judgement. When the 3 series were compared, the in-patient series contained the most definite cases, the outpatient series was intermediate, and the general population series was characterized mainly by below-threshold conditions. Disorders above the threshold point were classified using the CATEGO program. The clinical severity of the depressive disorders and anxiety states identified in this way in the 3 series was compared on the basis of symptom and syndrome profiles and PSE scores. As expected, the inpatients had the most severe, and the general population 'cases' the least severe disorders. It is suggested that the PSE-ID-CATEGO techniques can be used to help standardize certain aspects of case-finding and case-description in both referred and non-referred populations and thereby make the results of surveys more comparable.
对一系列年龄在65岁以下、居住在伦敦东南部同一地区的住院患者、门诊患者以及来自普通人群样本的女性,使用第九版《目前状况检查》(PSE)进行了检查。基于PSE症状的数量、类型和严重程度构建了一个“定义指数”(ID),以确定一个阈值点,超过该点就有足够的信息可将其分类为功能性精神病或神经症之一。该指数规定了8个疾病定义级别;“病例”的阈值点介于第4级和第5级之间。通过这种方式在普通人群系列中识别“病例”与整体临床判断高度一致。当对这三个系列进行比较时,住院患者系列包含最明确的病例,门诊患者系列处于中间水平,而普通人群系列主要以低于阈值的情况为特征。阈值点以上的疾病使用CATEGO程序进行分类。根据症状和综合征概况以及PSE评分,对在这三个系列中以这种方式识别出的抑郁症和焦虑症的临床严重程度进行了比较。正如预期的那样,住院患者的疾病最严重,而普通人群“病例”的疾病最不严重。建议PSE-ID-CATEGO技术可用于帮助规范转诊人群和非转诊人群中病例发现和病例描述的某些方面,从而使调查结果更具可比性。