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[抑郁症中的血浆和唾液地塞米松抑制试验。临床应用及动力学方法]

[Plasma and saliva DST (dexamethasone suppression test) in depression. Clinical applications and kinetic approach].

作者信息

Piollet I, Lepine J P, Guechot J, Philip E, Rouillon F, Fiet J, Lajeunesse C, Villette J M, Dreux C, Lemperiere T

出版信息

Encephale. 1984;10(6):279-80.

PMID:6529934
Abstract

Both plasmatic and salivary DST were simultaneously performed on a sample of 37 patients with a diagnosis of major depressive disorder (DMS III criteria): 22 primary depressions and 15 secondary depressions. Salivary DST showed a similar specificity but a decreased sensitivity in comparison with plasmatic DST. Essentially, the simultaneous use of both tests resulted in a better specificity for primary depression.

摘要

对37例诊断为重度抑郁症(依据《精神疾病诊断与统计手册》第三版标准)的患者样本同时进行了血浆地塞米松抑制试验(DST)和唾液DST:其中22例为原发性抑郁症,15例为继发性抑郁症。与血浆DST相比,唾液DST显示出相似的特异性,但敏感性降低。从本质上讲,同时使用这两种检测方法对原发性抑郁症具有更高的特异性。

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