Lygidakis N J
Acta Chir Scand. 1984;150(8):665-8.
Scanning electron microscopy was used to define the difference in incidence of morphologic changes between dilated and non-dilated common bile ducts in patients with choledocholithiasis. In the dilated ducts there were large, crater-like fenestrations in the epithelial surface, associated with focal epithelial sloughing. The incidence of such changes was significantly greater than in the non-dilated ducts. The mechanism of the changes is postulated to comprise biliary stasis and subepithelial infiltration of bile through epithelial fenestrations.
采用扫描电子显微镜来确定胆总管结石患者扩张和未扩张胆总管之间形态学改变发生率的差异。在扩张的胆管中，上皮表面有大的、火山口样的开窗，伴有局灶性上皮脱落。这种改变的发生率显著高于未扩张的胆管。推测这些改变的机制包括胆汁淤积以及胆汁通过上皮开窗进行的上皮下浸润。
