Waschke K, Lukowsky A, Schmechta H, Bürger W
Biomed Biochim Acta. 1984;43(11):1233-9.
Fractions of retroplacental sera containing pregnancy-associated alpha 2-glycoprotein (PAAG) inhibited the lymphocyte transformation. The inhibitory effect did not correlate to the amount of this protein. It remained even after a specific depletion of the PAAG without altering the composition of the other proteins in the sera fractions. These results rule out a suppressive activity of the PAAG in the lymphocyte transformation.
含有妊娠相关α2-糖蛋白(PAAG)的胎盘后血清组分可抑制淋巴细胞转化。这种抑制作用与该蛋白的量无关。即使在特异性去除PAAG后,这种抑制作用仍然存在,且血清组分中其他蛋白质的组成未发生改变。这些结果排除了PAAG在淋巴细胞转化中的抑制活性。