Riviera L, Bellotti M G, Valenti G
Chemioterapia. 1984 Apr;3(2):116-8.
The antifungal activity of the protiofate, a molecule derived from thiophene, was determined in vitro. For the testing, we determined the MIC values of 63 fungal strains (27 yeasts, 36 filamentous fungi, 14 of which were dermatophytes) at different pH values and different inoculum sizes. The comparison was made with econazole and clotrimazole. The results indicate that protiofate has good inhibitory activity vs yeasts at pH 7 and that it is active on filamentous fungi at pH 6.5 and 7.
对源自噻吩的分子丙硫酯的抗真菌活性进行了体外测定。在测试中，我们测定了63株真菌（27株酵母菌、36株丝状真菌，其中14株为皮肤癣菌）在不同pH值和不同接种量下的最低抑菌浓度（MIC）值。并与益康唑和克霉唑进行了比较。结果表明，丙硫酯在pH 7时对酵母菌具有良好的抑制活性，在pH 6.5和7时对丝状真菌有活性。
