Bogovski P A, Rooma M A, Kann J M
IARC Sci Publ. 1984(57):199-204.
N-Nitrosoproline (NPRO) formed intragastrically after ingestion of 8 mg/kg body weight sodium nitrate and the same amount of proline was determined in the sweat of six volunteers during intensive sweating in a Finnish sauna (60-80 degrees C). The amounts of sweat and NPRO and the concentrations of this compound varied between individual volunteers and in the same subjects in consecutive experiments. Females excreted higher concentrations of NPRO in smaller amounts of sweat. During the second hour after the start of intragastric nitrosation of proline, the concentrations and amounts of NPRO in sweat decreased rapidly.
摄入8毫克/千克体重的硝酸钠和等量脯氨酸后在胃内形成的N-亚硝基脯氨酸（NPRO），在芬兰桑拿房（60 - 80摄氏度）中剧烈出汗期间，对6名志愿者汗液中的NPRO进行了测定。汗液量、NPRO量以及该化合物的浓度在个体志愿者之间以及同一受试者的连续实验中有所不同。女性在较少汗液量中排泄出较高浓度的NPRO。在脯氨酸胃内亚硝化开始后的第二个小时，汗液中NPRO的浓度和量迅速下降。
