Demi M, Badocco R, Meneghetti G
Pediatr Med Chir. 1984 Jul-Aug;6(4):539-42.
The management of 11 cases of asymptomatic haematuria (E.A. in text) of which 1 macroscopic and 10 microscopic, involved a very accurate investigation on family medical history (focusing on haematuria, renal failure, deafness and atopy) as well as individual anamnesis (former events of E.A., concomitant and previous upper respiratory tract infections and allergic diseases) together with all laboratory and clinical tests on kidney functions. The first six months, the 24/hrs proteinuria, the "minute count" of urinary erythrocytes and the blood pressure were tested in all patients once a month, while, during the following 18 months, 3 tests only were carried out. All the subjects presented normal renal functions; for 2 of them the intravenous urography proved to be necessary because of a renal pain concomitant with haematuria while the audiogram was required for 1 subject only. After 2 years, the microscopic E.A. is still enduring in 3 patients: 2 of them recording haematuria in familial anamnesis and 1 suffering from similar episodes, long before we studied his case. None of them had to undergo the renal biopsy which the authors take into consideration only when E.A. is higher than 10,000.000 R.C./24 hrs and associated with high proteinuria and high complement decrease or when hereditary and concomitant to deafness (high frequences only).
对11例无症状血尿(文中简称E.A.)患者进行了治疗,其中1例为肉眼血尿,10例为镜下血尿。治疗过程中,对患者家族病史(重点关注血尿、肾衰竭、耳聋和特应性疾病)进行了非常精确的调查,同时询问了个人病史(既往E.A.病史、同时期及既往的上呼吸道感染和过敏性疾病),并进行了所有有关肾功能的实验室和临床检查。在最初的六个月里,每月对所有患者进行一次24小时蛋白尿、尿红细胞“计数”及血压检测,而在接下来的18个月里,仅进行了3次检测。所有患者的肾功能均正常;其中2例因血尿伴肾区疼痛而行静脉肾盂造影检查,仅1例患者进行了听力图检查。两年后,3例患者镜下血尿仍持续存在:其中2例家族病史中有血尿记录,1例在我们研究其病例之前很久就有类似发作。他们均未进行肾活检,作者仅在E.A.高于10,000,000红细胞/24小时且伴有高蛋白尿和补体显著降低,或与耳聋(仅高频耳聋)相关或遗传时才考虑进行肾活检。