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用于血液透析器复用的过氧乙酸临床研究。

Peracetic acid for reuse of hemodialyzers clinical studies.

作者信息

Berkseth R, Luehmann D, McMichael C, Keshaviah P, Kjellstrand C

出版信息

Trans Am Soc Artif Intern Organs. 1984;30:270-5.

PMID:6533895
Abstract

When Renalin was used for reprocessing, the incidences of headache and hypotension were reduced and no changes in serum chemistries were noted. Dialyzer appearance was superior to that achieved with formaldehyde but accompanied by decreases in clearance of urea, creatinine, vitamin B-12 and a fall in KUF. While long-term patient toxicity studies are not yet available, laboratory studies suggest potential problems with carcinogenicity similar to those erroneously attributed to formaldehyde. These data suggest that Renalin may be a suitable alternative to formaldehyde for reprocessing hemodialyzers.

摘要

使用Renalin进行再处理时,头痛和低血压的发生率降低,且未观察到血清化学指标有变化。透析器外观优于使用甲醛时的情况,但同时尿素、肌酐、维生素B - 12的清除率下降,超滤系数(KUF)降低。虽然尚未有长期的患者毒性研究,但实验室研究表明存在与甲醛类似的潜在致癌问题。这些数据表明,Renalin可能是用于血液透析器再处理的甲醛的合适替代品。

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