Brasnu D, Lacau Saint-Guily J, Parpounas C, Fabre A, Laccourreye H
Ann Otolaryngol Chir Cervicofac. 1984;101(8):573-8.
The authors analyse the results of treatment of 84 squamous cell carcinomas of the mobile portion of the tongue treated between 1961 and 1982. 64% of the patients treated were Stage I or II. The local recurrence rate was 13% at 5 years (6/43) for T1, T2. Recurrences were more frequent after interstitial radium therapy (17% at 5 years: 5/28) than after partial glossectomy performed at the outset (6.6% : 1.15). The treatment of stage NO remains controversial. The frequency of lymph node recurrences remains proportional to lymph node involvement by histology (NO, N-: no recurrences; NO, N+: 18.1%: 6/33) but seemed to be independent of the initial treatment of the regional nodes: no treatment, neck dissection with or without subsequent external radiotherapy. It is important to emphasize that lymph node recurrences contralateral to the tumour always occurred in the presence of initial homolateral lymphadenopathy with capsular rupture. Other oncological failures were frequent (35% : 20/56) at 5 years, grouping together visceral metastases (14.3% : 8/56) and second primary cancers in the upper respiratory/digestive tract (21.4% : 12/56).
作者分析了1961年至1982年间治疗的84例舌活动部鳞状细胞癌的治疗结果。接受治疗的患者中64%为I期或II期。T1、T2期患者5年局部复发率为13%（6/43）。间质镭疗后复发更常见（5年时为17%：5/28），高于一开始就进行部分舌切除术的患者（6.6%：1/15）。NO期的治疗仍存在争议。淋巴结复发频率与组织学上的淋巴结受累情况成正比（NO，N-：无复发；NO，N+：18.1%：6/33），但似乎与区域淋巴结的初始治疗无关：未治疗、有或无后续外照射的颈清扫术。需要强调的是，肿瘤对侧的淋巴结复发总是发生在初始同侧淋巴结病伴包膜破裂的情况下。5年时其他肿瘤学失败情况很常见（35%：20/56），包括内脏转移（14.3%：8/56）和上呼吸道/消化道的第二原发性癌症（21.4%：12/56）。
