Falcini F, Volpi M, Pierattelli M, Taccetti G, Pratesi G, Matucci Cerinich M
Pediatr Med Chir. 1984 Sep-Oct;6(5):703-7.
Systemic sclerosis is a diffuse disorder of connective tissue in which there are inflammatory, fibrotic and degenerative changes in the skin and many internal organs. We describe a case of systemic sclerosis type "acrosclerosis" in a six years old child with Raynaud's phenomenon and gastrointestinal involvement. In the course of illness he presented severe digital ulcerations in the hands and in the feet, responsive to a calcium channel blocking agent nifedipine treatment.
系统性硬化症是一种结缔组织的弥漫性疾病，其皮肤和许多内脏器官存在炎症、纤维化和退行性改变。我们描述了一例6岁患有雷诺现象和胃肠道受累的“肢端硬化症”型系统性硬化症病例。在病程中，他的手部和足部出现严重的指端溃疡，对钙通道阻滞剂硝苯地平治疗有反应。
