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醋酸苯汞中毒大鼠的血浆和血小板纤维蛋白稳定因子活性

Plasma and platelet fibrin-stabilizing factor activity in rats intoxicated with phenylmercuric acetate.

作者信息

Michalska M, Wierzbicki R

出版信息

Pol J Pharmacol Pharm. 1984 Nov-Dec;36(6):611-5.

PMID:6535154
Abstract

Effect of phenylmercuric acetate on the activity of rat plasma and platelet fibrin-stabilizing factor (FSF) was studied. The mercurial was administered to the animals intragastrically in a single dose of 17.9 mg Hg/kg or in repeated doses of 1.79 mg Hg/kg, twice a week for 152 days. The activities of the investigated fibrin-stabilizing factors were significantly increased in the case of intoxicated rats. Such an effect was observed in both types of the exposure.

摘要

研究了醋酸苯汞对大鼠血浆和血小板纤维蛋白稳定因子(FSF)活性的影响。给动物灌胃给予汞剂,单次剂量为17.9毫克汞/千克,或重复剂量为1.79毫克汞/千克,每周两次,共152天。在中毒大鼠中,所研究的纤维蛋白稳定因子的活性显著增加。在两种暴露类型中均观察到这种效应。

相似文献

1
Plasma and platelet fibrin-stabilizing factor activity in rats intoxicated with phenylmercuric acetate.醋酸苯汞中毒大鼠的血浆和血小板纤维蛋白稳定因子活性
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Effect of methylmercuric chloride (MMC) on fibrin polymerization.
Biol Trace Elem Res. 1993 May-Jun;37(2-3):157-64. doi: 10.1007/BF02783791.