McKenzie J A
Aust J Biol Sci. 1984;37(5-6):367-74. doi: 10.1071/bi9840367.
Populations of L. cuprina collected from adjacent sheep-grazing areas and rubbish tips in Victoria (Mansfield and Warrnambool) and New South Wales (Lismore) were tested for resistance to the insecticides diazinon and dieldrin. Populations from sheep-grazing areas had a significantly higher diazinon Rop-1 allele frequency than those from adjacent tips with the Victorian populations being more resistant than those from Lismore. Victorian sheep and tip populations had similar gene frequencies at the dieldrin resistance locus, but the Rdl allele frequency was significantly greater in the population at the tip than in the population from the sheep-grazing area at Lismore. The Rdl allele is at a higher frequency in flies from the Lismore area than in Victorian populations. The results at both loci are explained by a balance of selection and gene flow between sheep and tip populations and by selective differences between geographical areas. The exceptionally high frequency of the dieldrin Rdl allele in populations at the Lismore tip may be partially explained by the use of dichlorvos for fly control. Dosage mortality curve and genetic analyses suggest that dichlorvos (an organophosphorus compound) may select at the dieldrin resistance locus. Possible mechanisms for this are discussed. The consequences of genetic differentiation between L. cuprina populations within a region for an autocidal control program are considered.
对从维多利亚州（曼斯菲尔德和沃南布尔）以及新南威尔士州（利斯莫尔）相邻的绵羊放牧区和垃圾场采集的铜绿蝇种群进行了抗杀虫剂二嗪农和狄氏剂的测试。来自绵羊放牧区的种群中二嗪农Rop - 1等位基因频率显著高于相邻垃圾场的种群，其中维多利亚州的种群比利斯莫尔的种群更具抗性。维多利亚州绵羊和垃圾场种群在狄氏剂抗性位点的基因频率相似，但垃圾场种群中的Rdl等位基因频率显著高于利斯莫尔绵羊放牧区的种群。Rdl等位基因在利斯莫尔地区的苍蝇中频率高于维多利亚州的种群。两个位点的结果可以通过绵羊和垃圾场种群之间选择与基因流的平衡以及地理区域之间的选择差异来解释。利斯莫尔垃圾场种群中狄氏剂Rdl等位基因的异常高频率可能部分归因于使用敌敌畏来控制苍蝇。剂量死亡率曲线和遗传分析表明，敌敌畏（一种有机磷化合物）可能在狄氏剂抗性位点进行选择。讨论了可能的机制。考虑了一个区域内铜绿蝇种群之间的遗传分化对自灭控制计划的影响。
