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括约肌切除术对犬胆汁酸肠肝循环的影响。

Effects of sphincterectomy on bile acid enterohepatic circulation in dogs.

作者信息

Beher W T, Dienst S G, Lin G J, Stradnieks S

出版信息

Steroids. 1984 Jul;44(1):35-46. doi: 10.1016/s0039-128x(84)80014-8.

DOI:10.1016/s0039-128x(84)80014-8
PMID:6537043
Abstract

Relative rates of bile enterohepatic circulation (EHC) and bile acid pool distribution were compared in intact and sphincterectomized dogs with portacaval shunt. There was no significant difference in the rates of EHC or in the bile acid pool distribution in the groups of animals. Feeding and cholecystokinin administration caused similar increases in bile acid EHC rates in sphincterectomized and intact animals. It was concluded that the sphincter of Oddi has little or no effect on these aspects of bile acid metabolism in dogs.

摘要

在完整和行Oddi括约肌切除并伴有门腔分流的犬中,比较胆汁肝肠循环(EHC)的相对速率和胆汁酸池分布。两组动物的EHC速率或胆汁酸池分布没有显著差异。喂食和给予胆囊收缩素使行Oddi括约肌切除的动物和完整动物的胆汁酸EHC速率产生相似的增加。得出的结论是,Oddi括约肌对犬胆汁酸代谢的这些方面几乎没有影响。

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