法属圭亚那两个美洲印第安部落的组织相容性抗原。

Histocompatibility antigens in two American Indian tribes of French Guiana.

作者信息

Tchen P, Bois E, Feingold N, Grenand F, Degos L

出版信息

Tissue Antigens. 1978 Mar;11(3):315-9. doi: 10.1111/j.1399-0039.1978.tb01263.x.

DOI:10.1111/j.1399-0039.1978.tb01263.x

Abstract

Two South American Indian populations were typed for HLA antigens. In each, the individuals typed were related and their genealogies were known. Determination of their genotypes was done; there seemed to be neither excess nor deficiency in homozygotes. The antigens observed, A2, A9, Aw19.2 (Aw30-Aw31), A28 for the first locus and B5, Bw15, Bw35, Bw40 for the second locus are in accordance with those previously described for other South American Indians. The two populations belong to the same primary linguistic family Tupi-Guarani and they live in the same geographic area, but there was no intertribal marriage until recently. Genetic drift can explain the differences observed.

摘要

对两个南美印第安人群体进行了HLA抗原分型。在每个群体中，被分型的个体都有亲属关系且其谱系是已知的。对他们的基因型进行了测定；杂合子似乎既没有过多也没有不足。观察到的第一个位点的抗原A2、A9、Aw19.2（Aw30 - Aw31）、A28以及第二个位点的抗原B5、Bw15、Bw35、Bw40与先前描述的其他南美印第安人的抗原一致。这两个人群体属于同一个主要语言家族图皮 - 瓜拉尼语系，并且生活在同一地理区域，但直到最近才出现部落间通婚。基因漂变可以解释所观察到的差异。