Stiglick A, Woodworth I
Alcohol. 1984 Sep-Oct;1(5):413-5. doi: 10.1016/0741-8329(84)90013-2.
Naive food-restricted and food-satiated rats were given a choice between ethanol (8%, 16%, or 32%) and water for 22 hours/day over 14 days. On all days and at all concentrations, intakes of ethanol were significantly higher in the food-restricted animals. Doses consumed by these animals were highest when 32% ethanol was used, with a mean daily intake of 6.83 g/kg. Preference scores, calculated as the percent of total fluid intake as ethanol, were also much higher in the food-restricted animals. These findings demonstrate that the caloric value of ethanol may be an important factor in ethanol self-administration, but they do not rule out the possible importance of pharmacological effects.
将未接触过乙醇的食物受限和食物充足的大鼠置于乙醇（8%、16%或32%）和水之间进行选择，每天22小时，持续14天。在所有天数和所有浓度下，食物受限动物的乙醇摄入量均显著更高。当使用32%乙醇时，这些动物的摄入量最高，平均每日摄入量为6.83克/千克。以乙醇占总液体摄入量的百分比计算的偏好分数在食物受限动物中也高得多。这些发现表明，乙醇的热量值可能是乙醇自我给药的一个重要因素，但它们并不排除药理作用的潜在重要性。
