McMillan D E, Leander J D
Drug Alcohol Depend. 1978 Jul;3(4):227-34. doi: 10.1016/0376-8716(78)90076-5.
Rats could lever press 24 hours a day for 97 mg food pellets under a fixed-interval (FI) 90 second schedule. During the first 4 days, an ethanol solution was the only available fluid, after which both water and ethanol solutions were available. At ethanol concentrations (w/v) of 5%, 7.5% and l0%, total caloric intake and total fluid intake remained constant, while ethanol consumption was inversely proportional to the concentration of the solution. When the FI 90s schedule was changed to FI 45 s, or to FI 180 s, there were only small changes in total caloric intake, total fluid intake and in percentages of total fluid consumption and total caloric intake as ethanol. The data suggest that the intake of ethanol under this fixed-interval schedule depends more on the ethanol concentration than on the calories obtained from ethanol drinking.
在固定间隔90秒的时间表下，大鼠可以一天24小时按压杠杆获取97毫克的食物颗粒。在最初的4天里，仅提供乙醇溶液，之后水和乙醇溶液都可获取。在乙醇浓度（重量/体积）为5%、7.5%和10%时，总热量摄入和总液体摄入量保持恒定，而乙醇消耗量与溶液浓度成反比。当固定间隔90秒的时间表改为固定间隔45秒或180秒时，总热量摄入、总液体摄入量以及乙醇在总液体消耗量和总热量摄入中所占百分比仅有微小变化。数据表明，在这种固定间隔时间表下，乙醇摄入量更多地取决于乙醇浓度，而非从饮用乙醇中获取的热量。
