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关于重性精神病中催乳素的研究——参考精神分裂症中催乳素对应激的反应

Studies on prolactin in major psychoses--with reference to prolactin response to stress in schizophrenia.

作者信息

Tsuchiya K

出版信息

Folia Psychiatr Neurol Jpn. 1984;38(1):53-6. doi: 10.1111/j.1440-1819.1984.tb00354.x.

DOI:10.1111/j.1440-1819.1984.tb00354.x
PMID:6537392
Abstract

The serum prolactin concentrations of schizophrenics with delusions or hallucinations, hypomanics, depressives, alcoholics with and without psychotic symptoms were examined. Among them, only the serum prolactin concentrations of alcoholics with psychotic symptoms were significantly higher when compared to the normal controls. In a stress experiment, the alterations of serum prolactin seen in schizophrenics were significantly greater when compared to the normal controls. The results are discussed in connection with the neurochemical mechanisms for the emotional states caused by stress.

摘要

对伴有妄想或幻觉的精神分裂症患者、轻躁狂患者、抑郁症患者、有和没有精神病症状的酗酒者的血清催乳素浓度进行了检测。其中,只有有精神病症状的酗酒者的血清催乳素浓度与正常对照组相比显著更高。在一项应激实验中,与正常对照组相比,精神分裂症患者血清催乳素的变化显著更大。结合应激引起情绪状态的神经化学机制对结果进行了讨论。

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