Kuenen-Boumeester V, Hop W C, Blonk D I, Boon M E
Eur J Cancer Clin Oncol. 1984 Mar;20(3):337-45. doi: 10.1016/0277-5379(84)90079-8.
Applying morphometry on FNA smears may lead to meaningful prognostic subgrouping of breast carcinomas. A statistical analysis of the cytomorphometric and clinical data of 73 patients with breast carcinoma was performed. By multivariate analysis, taking into account various prognostic factors, it was shown that variations in nuclear area and the presence of axillary metastases were the most important prognosticators. By weighing these factors a prognostic score was obtained. According to that score the patients were classified into 4 score groups: the decreasing survival with increasing score was evident. The prognostic score was also related to the metastasis-free period. This prognostic scoring is relatively easy to perform, and can be done in routine pathology laboratories.
对细针穿刺抽吸涂片进行形态测量学分析可能会对乳腺癌进行有意义的预后亚组划分。对73例乳腺癌患者的细胞形态测量学和临床数据进行了统计分析。通过多变量分析，并考虑各种预后因素，结果显示核面积变化和腋窝转移的存在是最重要的预后指标。通过权衡这些因素获得了一个预后评分。根据该评分将患者分为4个评分组：随着评分增加生存率降低是明显的。预后评分也与无转移期相关。这种预后评分相对容易实施，并且可以在常规病理实验室中完成。
