Kakinuma R, Nishiwaki Y, Yano H, Kajita M, Nishiyama H, Kitaya T, Matsuyama T, Fukushima J
Gan No Rinsho. 1984 Apr;30(4):344-8.
Among patients with lung cancer, those having PS 4 ( Performance Status 4) and cancer pain received " Pyrecon ", a psychotropic agent, consisting of promethazine hydrochloride ( Pyrethia ) and chlorpromazine hydrochloride ( Contomin ). A mixture of 125 mg of Pyrethia and 50 mg of Contomin was diluted in 500 ml of regular IV solution and given through the central vein at a rate of 20 ml/hr. Pyrecon was found to be effective in patients with severe cancer pain in whom Brompton cocktail was ineffective. Pyrecon was also effective in patients whose daily life rhythm was unsteady due to insomnia caused by anxiety or unrest. We suggest that Pyrecon is effective in the treatment of cancer pain.
在肺癌患者中，那些身体状况评分为4分（PS 4）且患有癌痛的患者接受了一种名为“Pyrecon”的精神药物治疗，该药物由盐酸异丙嗪（Pyrethia）和盐酸氯丙嗪（Contomin）组成。将125毫克的Pyrethia和50毫克的Contomin混合在500毫升的常规静脉输液中，并通过中心静脉以每小时20毫升的速度给药。结果发现，Pyrecon对使用布罗姆pton鸡尾酒疗法无效的重度癌痛患者有效。Pyrecon对因焦虑或不安引起失眠而导致日常生活节奏不稳定的患者也有效。我们认为Pyrecon在癌痛治疗中是有效的。
