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右旋苯丙胺和哌甲酯对多动症儿童的副作用——简要综述

Side effects of dextroamphetamine and methylphenidate in hyperactive children--a brief review.

作者信息

Golinko B E

出版信息

Prog Neuropsychopharmacol Biol Psychiatry. 1984;8(1):1-8. doi: 10.1016/0278-5846(84)90129-5.

Abstract

Four of the most commonly reported side effects of dextroamphetamine ( Dexedrine ) and methylphenidate (Ritalin), viz., anorexia, insomnia, stomach pains, and weight loss, were reviewed, with special attention to growth suppression accompanying weight loss. The available evidence indicates that the effects of insomnia, anorexia, and stomach pains are transient and diminish as treatment continues and as medication is properly managed. There is evidence for growth suppression accomapnying weight loss, and possibly some suppression of stature, but these effects are not long-lasting and, from existing evidence, seem to have little effect on adult height or weight.

摘要

对右旋苯丙胺(德克西得林)和哌醋甲酯(利他林)最常报告的四种副作用,即厌食、失眠、胃痛和体重减轻进行了综述,特别关注伴随体重减轻的生长抑制。现有证据表明,失眠、厌食和胃痛的影响是短暂的,随着治疗的持续和药物的合理管理会逐渐减轻。有证据表明体重减轻会伴随生长抑制,可能还会有一定程度的身高抑制,但这些影响并非持久的,而且从现有证据来看,似乎对成人身高或体重影响不大。

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