Khuffash F A, Barakat M H, Majeed H A, White A G, Beseda A J
Gut. 1984 Sep;25(9):1009-12. doi: 10.1136/gut.25.9.1009.
A pair of monozygotic twin girls with coeliac disease is reported. The diagnosis was made on clinical and biochemical evidence of malabsorption, characteristic histological findings, and clinical, biochemical, and histological response to gluten elimination. Monozygosity was established on finding a single placenta at birth, exact similarity of physical appearance, similar blood group, and histocompatibility antigens, and negative reaction in mixed lymphocyte culture. This is one of six well documented cases of coeliac disease in monozygotic twins and may throw light on the importance of genetic and environmental factors in the causation and expression of the disease.
报道了一对患有乳糜泻的单卵双胞胎女孩。根据吸收不良的临床和生化证据、特征性组织学表现以及对消除麸质的临床、生化和组织学反应做出诊断。通过出生时发现单一胎盘、外貌完全相似、血型相同、组织相容性抗原相同以及混合淋巴细胞培养呈阴性反应确定为单卵双生。这是单卵双胞胎中记录良好的六例乳糜泻病例之一，可能有助于阐明遗传和环境因素在该疾病病因和表现中的重要性。
