Fallahi S, Collins R D, Miller R K, Halla J T
J Rheumatol. 1984 Aug;11(4):526-9.
Two patients with rheumatoid arthritis (RA) and sarcoidosis illustrate the dilemmas posed by their coexistence in the same patient. The first patient with classical RA developed iridocyclitis, interstitial lung disease and cranial neuropathies, initially attributed to extraarticular rheumatoid disease. Subsequent lung and skin biopsy revealed many granulomas consistent with sarcoidosis whereas synovium revealed changes typical for RA. In the second patient with cutaneous and pulmonary sarcoidosis development of persistent erosive polyarthritis and a subcutaneous nodule with typical pathology permitted the diagnosis of coexistent RA. These cases emphasize that uveitis alone or multiple cranial neuropathies are not features of RA and symptomatic interstitial lung disease in patients with RA warrants further investigation.
两名患有类风湿性关节炎（RA）和结节病的患者说明了这两种疾病共存于同一患者时所带来的困境。首例患有典型RA的患者出现了虹膜睫状体炎、间质性肺病和颅神经病变，最初被归因于关节外类风湿性疾病。随后的肺部和皮肤活检显示出许多与结节病相符的肉芽肿，而滑膜则显示出RA的典型变化。第二例患有皮肤和肺部结节病的患者出现了持续性侵蚀性多关节炎以及具有典型病理特征的皮下结节，从而得以诊断出并存的RA。这些病例强调，单纯的葡萄膜炎或多发性颅神经病变并非RA的特征，RA患者出现有症状的间质性肺病需要进一步检查。
