Sverbivus Ia A
Vopr Pitan. 1978 Mar-Apr(2):47-9.
Tests conducted on rats kept for 2 months on a food ration deficient of sodium demonstrated a reduced concentration of nicotinic acid in the liver, kidneys, heart, lungs, brain and the muscles. In these conditions of the experiment intraperitoneal administration of 14C-nicotinic acid resulted in a greater incorporation of the tag in the organs of test animals as compared with controls. A particularly clearcut increase of such incorporation occurs with a 12-hour exposure.
对食用缺钠日粮两个月的大鼠进行的测试表明,其肝脏、肾脏、心脏、肺、大脑和肌肉中的烟酸浓度降低。在这些实验条件下,与对照组相比,腹腔注射14C-烟酸导致测试动物器官中标记物的掺入量增加。在12小时的暴露下,这种掺入量会有特别明显的增加。