[Dysplastic urothelial changes in patients with bladder cancer].

The authors treated 238 patients with urinary bladder tumours in 4 years. In each case the transurethral resection formed an integrae part of the treatment plan in the form of a diagnostic, curative or palliative TUR. The transurethral intervention in 152 cases was carried out with differentiated resection technique according to Bressel, in 137 cases mapping was also made of 9 different points. By this technique detailed information was obtained about the pathological lesion of the mucosa which appeared healthy by endoscopy in 122 patients. Precancerous lesions which can form the basis for later malignant epithelial proliferation were found in 50,9% of the patients. The number and severity of the dysplastic lesions showed close correlation with the histological differentiation grade of the tumour.