Harinasuta C, Harinasuta T
Arzneimittelforschung. 1984;34(9B):1164-7.
Opisthorchis viverrini has been found to be the only species of liver fluke in Thailand. The morphology is similar to that of O. felineus, but it has more deeply lobated testes, situated near the ovary. The appearance and distribution of the vitellaria with few granular clumps and the shorter and wider egg closely resemble that of C. sinensis. The adult worms live in the biliary system. Eggs pass out in faeces. On reaching water the eggs are eaten by snails, the first intermediate host. In the snail the miracidia hatch and develop further through the stages of sporocysts, rediae and cercariae in six to eight weeks. The cercariae then leave the snail, penetrate into susceptible fresh water fish, encyst in the muscle and develop into metacercariae, and infective stage, in six weeks. When ingested by man or animal the metacercariae excyst in the duodenum or jejunum and then migrate to the bile duct. They become mature within four weeks and begin to produce eggs. The life span of the fluke is over 10 years. The snail intermediate hosts are Bithynia goniomphalus, B. funiculata and B. siamensis. Many species of cyprinoid fish serve as second intermediate host; Cyclocheilichthys siaja is the most important. Cats, dogs and many fish eating mammals are definitive hosts. Man and animals acquire infection by eating raw fish containing metacercariae cysts. In Northeast Thailand "Koi-Pla" is the most popular raw fish dish. In 1980-1981 the prevalence in the north, northeast, centre and south of Thailand was 5.59, 34.60, 6.34, and 0.01%, respectively, with an overall prevalence of 14% or 7 million people.
泰国已发现麝猫后睾吸虫是唯一的肝吸虫种类。其形态与猫后睾吸虫相似，但睾丸分叶更深，位于卵巢附近。卵黄腺外观及分布特点为颗粒团块较少，虫卵更短更宽，这与华支睾吸虫极为相似。成虫寄生于胆管系统。虫卵随粪便排出。虫卵入水后被第一中间宿主蜗牛吞食。在蜗牛体内，毛蚴孵出，并在6至8周内历经胞蚴、雷蚴和尾蚴阶段进一步发育。尾蚴随后离开蜗牛，钻入易感淡水鱼体内，在肌肉中形成囊蚴，并在6周内发育为感染期的后尾蚴。人或动物摄入后，后尾蚴在十二指肠或空肠脱囊，然后迁移至胆管。它们在4周内发育成熟并开始产卵。吸虫的寿命超过10年。蜗牛中间宿主为贡氏沼螺、有沟沼螺和暹罗沼螺。多种鲤科鱼类为第二中间宿主；暹罗结鱼最为重要。猫、狗及许多食鱼哺乳动物为终宿主。人和动物因食用含有后尾蚴囊蚴的生鱼而感染。在泰国东北部，“生腌鱼”是最受欢迎的生鱼菜肴。1980 - 1981年，泰国北部、东北部、中部和南部的感染率分别为5.59%、34.60%、6.34%和0.01%，总体感染率为14%，即700万人。
